Process

Our process experience in the various pharmaceutical and food & beverage processing sector fields allowed us to develop a proven approach that prioritizes the manufacturing and process needs in the design process.

We approach our process projects by first developing an in-depth understanding of the process itself and the production goals. These characteristics play a key role in the development of the installation program. We pay special attention to the level of uncertainty of the basic characteristics, and to the level of flexibility required by the project. Our knowledge of the industry allows us to identify the gray areas, and to establish plausible hypotheses for the installation’s operational characteristics.

Through our process experience we have established a large process equipment acquisition and installation cost database, which allows us to estimate the cost of projects more precisely on a design or detailed basis.

To complete process mandates, Laporte uses the following design reference tools:

Conceptual phase

  • P&ID (PFD, BFD, EFD)
  • Process simulation
  • Material and energy balance
  • Design development

Preliminary design phase

  • Preliminary P&ID’s
  • Development drawings
  • Purchasing specifications
  • Performance specifications

Detailed design phase

  • Detailed P&ID’s
  • Installation drawings
  • Isometric
  • 3D drawings
  • Installation specifications

FIELDS OF EXPERTISE

Bio-process

  • Fermentation
  • Cell culture
  • Inactivation
  • Chromatography
  • Tangential flow filtration
  • Centrifugation
  • Microfiltration
  • Cleaning-in-place
  • Sterilization

Pharmaceutical

  • Aseptic formulation
  • Liquid formulation
  • Cream and ointment formulation
  • Solid formulation
  • Cytotoxic formulation
  • Aseptic filling
  • Solid and liquid filling
  • Blister packaging
  • Cleaning-in-place
  • Lyophilization
  • Sterilization
  • Aseptic filling
  • Packaging
  • Insulators
Food & beverage processing

  • Fermentation
  • Aseptic filling
  • Flash pasteurization
  • Evaporation
  • Ultrafiltration
  • Centrifugation
  • Extrusion
  • Drying
  • Formulation and baking
  • Packaging
  • Cleaning-in-place
  • Sanitization

Active pharmaceutical ingredients

  • Chemical reaction
  • Distillation
  • Filtration
  • Centrifugation
  • Drying
  • Lyophilization

Bulk storage

  • Solvents
  • Pharmaceutical excipients
  • Solids
  • Food products (liquid, solid)

Effluent treatment

  • Liquid (neutralization, thermal inactivation, chemical inactivation, dissolved air flotation system)
  • Gas (air cleaning device, dust extractor, thermal and catalytical oxidation, activated carbon)
  • Gas (CO2, He, N2, Ar, Propane, O2, H2; recovery, compression, purification, liquefaction)
  • Containment systems (very active products, cytotoxic, biological, isolators, chemical and biological hoods)